*This statement is a creative representation of the comparison between Becosules capsules and Oranges and does not represent the true nature of using the product. $ Indicated in the treatment of patients with deficiencies of or increased requirement for, vitamin B-complex, and vitamin C. ^2X here refers to 2-times. † Average vitamin C content of a medium-sized Orange is 70 mg.2 ‡ Good health here refers to health benefits from treatment for addressing deficiencies of, or increased requirement for, vitamin B-complex, and vitamin C. $$ 1 Capsule Daily or as directed by the Physician1 . References: 1. Becosules Capsules LPDBCC092017. 2. Vitamin C Fact-sheet for Healthcare Professionals, NIH Office of Dietary Supplements, Available on: https://ods.od.nih.gov/factsheets/VitaminC-HealthProfessional/, Last accessed on: 10th June, 2021. 3. Zhang Y, Zhou Wei-e et al, A Review of the Extraction and Determination Methods of Thirteen Essential Vitamins to the Human Body: An Update from 2010, Molecules. 2018, 23, 1484, doi:10.3390/molecules23061484 Summary of Prescribing Information of Becosules® Capsules Before prescribing, please refer to the full prescribing information of Becosules® Capsules Generic name: B-Complex Forte with Vitamin C Capsules. Brand name of product: BECOSULES® CAPSULES. Indications: Becosules capsules are indicated in the treatment of patients with deficiencies of, or increased requirement for, vitamin B-complex, and vitamin C in conditions such as anorexia, diabetes mellitus, obesity and alcoholism, during treatment with antimicrobials which alter normal intestinal flora, prolonged diarrhea , chronic gastro-intestinal disorders, febrile illness, acute or chronic infections, surgery, burns and fractures, stomatitis, glossitis, cheilosis, paraesthesias, neuralgia and dermatitis and micronutrient deficiencies during pregnancy or lactation. Pharmaceutical Form: Each capsule contains: Thiamine Mononitrate I.P. 10 mg, Riboflavin I.P. 10 mg, Pyridoxine Hydrochloride I.P. 3 mg, Vitamin B12 I.P. (as STABLETS 1:100) 15 mcg ,Niacinamide I.P. 100 mg, Calcium Pantothenate I.P. 50 mg, Folic Acid I.P. 1.5 mg, Biotin U.S.P. 100 mcg, Ascorbic Acid I.P. (as coated) 150 mg Dosage: One capsule daily, or as directed by the physician. Method of Administration: Oral Contraindications: Hypersensitivity to any of the ingredients of Becosules Capsules. Warnings and Precautions: The use of Becosules capsules in patients with deficiency or increased requirement of vitamins B-complex, and vitamin C should be accompanied by specific therapy for the primary illness. Treatment with Becosules capsules should be continued only until the deficiency is corrected or the need for supplementation exists. Pyridoxine in Becosules capsules may reduce the therapeutic effects of levodopa in Parkinson's disease. Riboflavin in Becosules capsules may color the urine yellow. During treatment with Becosules capsules, the urine may give a false positive result for sugar by Benedict's test because of the presence of ascorbic acid. Therefore, a test not affected by ascorbic acid, should be used. In pernicious anemia, folic acid in Becosules capsules may correct anemia but aggravate neurological lesion. Use in Special population: In pregnant and lactating women, dosing should be per recommended allowances for their condition as advised by physician, since their vitamin requirements may be higher. Adverse reactions: Hypersensitivity reactions have been reported with thiamine and folic acid, although these are rare. Drug interactions: Although the clinical importance is unknown, thiamine reportedly may enhance the effect of neuromuscular blocking agents. The rate and extent of absorption of riboflavin are reportedly affected by propantheline bromide. Pyridoxine hydrochloride reverses the therapeutic effects of levodopa by accelerating peripheral metabolism of levodopa. Absorption of vitamin B12 from the GI tract may be decreased by aminoglycoside antibiotics, colchicine, extended-release potassium preparations, amino salicylic acid and its salts and anticonvulsants (e.g., phenytoin, phenobarbital, primidone). Prednisone has been reported to increase the absorption of vitamin B12 in a few patients with pernicious anemia. The clinical importance of these findings is unknown. Concurrent administration of chloramphenicol and vitamin B12 reportedly may antagonize the hematopoietic response to vitamin B12 in vitamin B12 deficient patients. The hematologic response to vitamin B12 in patients receiving both drugs should be carefully monitored and alternate anti-infectives should be considered. Niacin reportedly potentiates the hypotensive effect of ganglionic blocking drugs. Overdose: B-Complex vitamins are water soluble and excess vitamins are expelled in urine. Hence overdose is very rare. Storage Condition: Store below 25˚C, in a dry place. Adapted from- LPDBCC092017.
Becosules® capsules Trademark Proprietor: Pfizer Products Inc. USA. Licensed User: Pfizer Limited, India Full prescribing information available on request Pfizer Limited, The Capital – A Wing, 1802, 18th Floor, Plot No. C-70, G Block, Bandra-Kurla Complex, Bandra (East), Mumbai 400 051, India.